NABP NAPLEX North American Pharmacist Licensure Examination Exam Exam Practice Test Questions

• Question 1

  When does the newer chronic kidney disease (CKD) guidelines recommend stopping metformin?

  • When the estimated glomerular filtration (eGFR) is <30 mL/min/1.73 m2
  • When estimated glomerular filtration (eGFR) is <50 mL/min/1.73 m2
  • When creatinine clearance <30 ml/min
  • When creatinine clearance <50 ml/min
  • When serum creatinine is <1.8 mg/dL

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• Question 2

  A 27-year-old female with ovarian cancer is undergoing chemotherapy. She develops subsequent renal failure.Which of the following drugs is most likely responsible for this?

  • Cyclophosphamide
  • Bleomycin
  • Cisplatin
  • Vinblastine
  • Vincristine

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• Question 3

  CJ is a 69-year-old male with a history of diabetes, hypertension and hypercholesterolemia. His fasting lipid profile is TC 530 mg/dL; LDL-C 125; HDL-C 48 mg/dL; and TG 640 mg/dL. His A1c 8.1, calculate creatinine clearance is 65mls/hr, BP 135/80 mm Hg, HR 70 beats /min.His current medications include metformin 1000mg po bid, lisinopril 20mg daily, sitagliptin 50mg bid and atorvastatin 40mg daily.What is the best pharmacological agent to initiate on CJ?

  • Increase atorvastatin to 80mg
  • Niacin 500mg twice daily
  • Fenofibrate 162mg daily
  • Gemfibrozil 600mg twice daily
  • Fish oil 500mg twice daily

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• Question 4

  A physician orders Dopamine 5 mcg/kg/min. The concentration of the Dopamine IV bag is 400 mg in 250 D5W. The patient's weight is 168 lbs. Calculate the infusion rate in mL/hr.

  • 10.2mls/hr
  • 5.2mls/hr
  • 14.29mls/hr
  • 22.4mls/hr
  • 0.17mls/hr

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• Question 5

  Which of the following antidiabetic medication works by inhibiting carbohydrate breakdown?

  • Acarbose
  • Metformin
  • Dapagliflozin
  • Pioglitazone
  • Sitagliptin

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